PF-3052334 is an orally active, hepatically selective HMG-CoA reductase inhibitor with an IC 50 of 1.9 nM. PF-3052334 inhibits cholesterol synthesis, with IC 50 values of 0.9 and 730 nM in hepatocytes and muscle cells, respectively. PF-3052334 can be used to study hypercholesterolemia.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > HMG-CoA Reductase (HMGCR)
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