Ac-FLTD-CMK

Overview

Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 ( IC 50 of 46.7 nM), caspases-4 ( IC 50 of 1.49 μM), caspases-5 ( IC 50 of 329 nM), and caspases-11 , but not the apoptotic caspases such as caspase-3 .

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Pyroptosis

Product Information

• Catalog No.: HY-111675
• CAS No.: 2376255-48-8
• Molecular Formula: C26H37ClN4O8
• Molecular Weight: 569.05
• Purity: 99.18%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (4.39 mM); Clear solution
• Availability: In-stock

Source

Original product source