PROTAC B-Raf degrader 1

Overview

PROTAC B-Raf degrader 1 (compound 2) is a proteolysis targeting chimera ( PROTAC ) for the degradation of B-Raf based on Cereblon ligand with anti-cancer activity. (Pink: Raf ligand ( HY-12037A ); Blue: Cereblon ligand ( HY-10984 ); Black: linker ( HY-Y0966 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Raf

Product Information

• Catalog No.: HY-111758
• CAS No.: 2364367-27-9
• Molecular Formula: C36H37N5O12S
• Molecular Weight: 763.77
• Purity: 99.78%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (3.27 mM); Clear solution
• Availability: In-stock

Source

Original product source