SNIPER(ABL)-058, conjugating Imatinib ( ABL inhibitor ) to LCL161 derivative ( IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC 50 of 10 μM.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > SNIPERs | Products > Signaling Pathways > Bcr-Abl
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