SNIPER(ABL)-033

Overview

SNIPER(ABL)-033, conjugating HG-7-85-01 ( ABL inhibitor ) to LCL161 derivative ( IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC 50 of 0.3 μM (ABL inhibitor: HY-15814; ABL inhibitor activity control: HY-131178; E3 ligase ligand: HY-128808; linker: HY-130500; E3 ligase ligand + linker: HY-128819).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > SNIPERs | Products > Signaling Pathways > Bcr-Abl

Product Information

• Catalog No.: HY-111871
• CAS No.: 2222354-18-7
• Molecular Formula: C61H73F3N10O9S2
• Molecular Weight: 1211.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source