Lenacapavir sodium

Overview

Lenacapavir (GS-6207) sodium is an HIV-1 capsid inhibitor. Lenacapavir sodium binds to the interface between capsid hexamers and CA monomers, disrupts capsid assembly and viral maturation, inhibits nuclear translocation of HIV-1 DNA, interferes with CA-mediated protein-protein interactions, reduces the formation of 2-LTR circles and pre-integration proviruses, induces aberrant capsids, and decreases the production of mature HIV-1 . Lenacapavir sodium exhibits activity against a variety of HIV-1 subtypes and clinical isolates. Lenacapavir sodium is applicable to research related to human immunodeficiency virus type 1 ( HIV-1 ) infection .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > HIV Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > HIV

Product Information

• Catalog No.: HY-111964A
• CAS No.: 2283356-12-5
• Molecular Formula: C39H31ClF10N7NaO5S2
• Molecular Weight: 990.26
• Purity: 99.86%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 1.3 mg/mL (1.31 mM); Clear solution
• Availability: In-stock

Source

Original product source