Shield-1

Overview

Shield-1 (Shld1) is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12 ( FKBP ), and reverses the instability by binding to mutated FKBP (mtFKBP) , allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize proteins tagged with a mutated FKBP12-derived destabilization domain (DD).

Application

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Product Information

• Catalog No.: HY-112210
• CAS No.: 914805-33-7
• Molecular Formula: C42H56N2O10
• Molecular Weight: 748.90
• Purity: 99.55%
• Storage: -80°C, stored under nitrogen
• Solubility: ≥ 5.25 mg/mL (7.01 mM); Clear solution
• Availability: In-stock

Source

Original product source