SR 16832

Overview

SR 16832 is a dual-site covalent, orthosteric and allosteric PPARγ antagonist. SR 16832 activates the TGF-β signaling pathway and upregulates the expression of Vimentin and Fibronectin ( Fibronectin ). SR 16832 is toxic to bronchial epithelium. SR 16832 can be used in research related to type 2 diabetes and pulmonary fibrosis.

Application

Products | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Type 2 Diabetes | Products > Disease Areas > Lung Fibrosis | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > PPAR | Products > Signaling Pathways > TGF-beta/Smad

Product Information

• Catalog No.: HY-112247
• CAS No.: 2088135-12-8
• Molecular Formula: C17H12ClN3O4
• Molecular Weight: 357.75
• Purity: 99.58%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source