MK2-IN-3 hydrate

Overview

MK2-IN-3 hydrate (compound 16) is an orally active, selective, and ATP-competitive MAPKAP-K2 (MK-2) inhibitor with an IC 50 of 8.5 nM.MK2-IN-3 hydrate is exceptional selectivity against MK-3 ( IC 50 =0.21 μM), MK-5 ( IC 50 =0.081 μM), ERK2 ( IC 50 =3.44 μM), MNK1 ( IC 50 =5.7 μM) as well as CDK2 , JNK2 , IKK2, MSK1, and MSK2.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > MAPKAPK2 (MK2)

Product Information

• Catalog No.: HY-112457
• CAS No.: 1186648-22-5
• Molecular Formula: C21H18N4O2
• Molecular Weight: 358.39
• Purity: 99.08%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source