dBET6

Overview

dBET6 is a highly potent, selective and cell-permeable PROTAC connected by ligands for Cereblon and BET , with an IC 50 of 14 nM, and has antitumor activity. (Pink: BET ligand ( HY-78695 ); Blue: Cereblon ligand ( HY-103596 ); Black: linker).

Application

Products | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Epigenetic Reader Domain

Product Information

• Catalog No.: HY-112588
• CAS No.: 1950634-92-0
• Molecular Formula: C42H45ClN8O7S
• Molecular Weight: 841.37
• Purity: 99.90%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 2.5 mg/mL (2.97 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source