PF-06815345 is an orally active and potent inhibitor of proprotein convertase subtilisin/kexin type 9 ( PCSK9 ) with an IC 50 value of 13.4 μM. PF-06815345 significantly decreases the PCSK9 level in vivo in mouse.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > PCSK9
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