NAMPT inhibitor-linker 1

Overview

NAMPT inhibitor-linker 1 is a agent-linker conjugates for ADC , composed of an NAMPT inhibitor as a payload, and a linker. ADC-3 consists of an NAMPT inhibitor-linker 1 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressing cell lines such as GIST-T1 and NCI-H526 cells, with IC 50 s of <3 pM and 9 pM, respectively.

Application

Products | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > Drug-Linker Conjugates for ADC

Product Information

• Catalog No.: HY-112615
• CAS No.: 2241019-57-6
• Molecular Formula: C36H37FN6O6
• Molecular Weight: 668.71
• Purity: 99.27%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 1.25 mg/mL (1.87 mM); Clear solution
• Availability: In-stock

Source

Original product source