OPC 33540

Overview

OPC-33540 is a highly selective and competitive PDE3 inhibitor with IC 50 values of 0.32 nM ( PDE3A ) and 1.5 nM ( PDE3B ). OPC-33540 exhibits IC 50 s against PDE1 , PDE2 , PDE4 , PDE5 , and PDE7 of 42.9, 52.3, 100.8, 2.5, and 51.3 μM, respectively. OPC-33540 significantly enhances cAMP accumulation in platelets and effectively inhibits thrombin-induced platelet aggregation. OPC-33540 can be used in antithrombotic studies.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Phosphodiesterase (PDE)

Product Information

• Catalog No.: HY-112631
• CAS No.: 189362-27-4
• Molecular Formula: C27H39N3O4
• Molecular Weight: 469.62
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source