25-Hydroxycholesterol

Overview

25-Hydroxycholesterol (25-OHC) is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC 50 ≈65 nM) and selective suppressor of IgA production by B cells.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-113134
• CAS No.: 2140-46-7
• Molecular Formula: C27H46O2
• Molecular Weight: 402.65
• Purity: 99.65%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 0.5 mg/mL (1.24 mM); Clear solution
• Availability: In-stock

Source

Original product source