12-HETE-d 8

Overview

12-HETE-d 8 is the deuterium labeled 12-HETE. 12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-κB through the integrin-linked kinase (ILK) pathway.12-HETE has both anti-thrombotic and pro-thrombotic effects. 12-HETE is a neuromodulator.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-113439S
• CAS No.: 2525175-25-9
• Molecular Formula: C20H24D8O3
• Molecular Weight: 328.52
• Purity: 98.03%
• Storage: Solution, -20°C, 2 years
• Availability: In-stock

Source

Original product source