Lipoxin A4

Overview

Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways. Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC 50 value of 25.74 nM.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-113509
• CAS No.: 89663-86-5
• Molecular Formula: C20H32O5
• Molecular Weight: 352.47
• Purity: 98.0%
• Storage: Solution, -20°C, 1 year
• Availability: In-stock

Source

Original product source