GSK2324 (Compd 1c) is a FXR agonist for diabetes study, with an EC 50 of 120 nM. GSK2324 exhibits t 1/2 values of 84 min (mouse), 170 min (rat), 110 min (beagle) and 120 min (cyno), respectively.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > FXR
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