Ageladine A dihydrochloride

Overview

Ageladine A dihydrochloride is an inhibitor of matrix metalloproteinase ( MMP ) isolated from the marine sponge Agelas nakamurai , possessing anti-angiogenic activity. Ageladine A dihydrochloride not only inhibits MMP-2 but also MMP-1 , MMP-8 , MMP-9 , MMP-12 , and MMP-13 , with IC 50 values of 4.65 μM, 2.79 μM, 907.12 nM, 1.83 μM, 767.57 nM, and 1.09 μM, respectively. Additionally, Ageladine A dihydrochloride is a pH-sensitive membrane-permeable dye that emits fluorescence in the blue-green range upon UV excitation, featuring a maximum absorption peak at 370 nm. Furthermore, Ageladine A dihydrochloride serves as a reliable and stable fluorescent pH sensor for detecting changes in intracellular pH values.

Application

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Product Information

• Catalog No.: HY-113621B
• CAS No.: 2757574-06-2
• Molecular Formula: C10H9Br2Cl2N5
• Molecular Weight: 429.93
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source