L-656224 is an orally active, potent and selective inhibitor of leukotriene biosynthesis in intact rat and human leukocytes and CXBG mastocytoma cells ( IC 50 values, 18-240 nM) and of human leukocyte and porcine leukocyte 5-lipoxygenase ( IC 50 , 4 x 10 -7 M). L-656224 is promising for research of asthma and peripheral analgesic agents.
Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > Lipoxygenase
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