BC-1485 is a small molecule inhibitor of Fibrosis-inducing E3 ligase 1 (FIEL1) . BC-1485 protects PIAS4 from ubiquitin-mediated degradation. BC-1485 decreases α-SMA , BAL and CXCL1 . BC-1485 ameliorates fibrotic lung injury in murine models.
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