NVS-ZP7-4

Overview

NVS-ZP7-4 is an inhibitor of the zinc transporter SLC39A7 (ZIP7) and indicates ER zinc levels. ZIP7 is an active molecular node in the Notch pathway and mediates ferroptosis . NVS-ZP7-4 induces ER stress and exerts a certain ferroptosis-inhibiting effect, reduces Erastin ( HY-15763 )-induced cell death.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Ferroptosis | Products > Signaling Pathways > SLC39 (Zinc Transporter)

Product Information

• Catalog No.: HY-114395
• CAS No.: 2349367-89-9
• Molecular Formula: C28H28FN5OS
• Molecular Weight: 501.62
• Purity: 98.85%
• Storage: -20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.08 mg/mL (4.15 mM); Clear solution
• Availability: In-stock

Source

Original product source