SJFδ

Overview

SJFδ is a 10-atom linker PROTAC based on von Hippel-Lindau ligand. SJFδ degrades p38δ with a DC 50 of 46.17 nM, but does not degrade p38α , p38β , or p38γ . (Pink: p38δ ligand ( HY-45124 ); Blue: VHL ligand ( HY-151227 ); Black: linker ( HY-133143 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-114405
• CAS No.: 2254609-23-7
• Molecular Formula: C62H63F2N7O12S
• Molecular Weight: 1168.27
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source