Tiazofurin

Overview

Tiazofurin (NSC 286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent inhibitor of IMP dehydrogenase ( IMPDH ) . Tiazofurin enhances the autosecretion of IL-6 in K562 cells. Tiazofurin also has anti- orthopoxvirus and anti-variola activities. Tiazofurin can be used for the study of leukemia and lung cancer .

Application

Products | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Viral Infection | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Depression | Products > Disease Areas > Pain | Products > Disease Areas > Orthopoxvirus Infection | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Neurological Disease | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Nucleoside Antimetabolite/Analog | Products > Signaling Pathways > Orthopoxvirus

Product Information

• Catalog No.: HY-114570
• CAS No.: 60084-10-8
• Molecular Formula: C9H12N2O5S
• Molecular Weight: 260.27
• Purity: 99.82%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source