AFN-1252 tosylate

Overview

AFN-1252 (API-1252) tosylate is an orally active and selective inhibitor of FabI , an essential enzyme in fatty acid biosynthesis in Staphylococcus spp. AFN-1252 tosylate exhibits exquisite and highly selective activity against Staphylococcus spp. AFN-1252 tosylate exhibits typical MIC 90 values of 0.015 μg/ml against diverse clinical isolates of S. aureus . AFN-1252 tosylate is efficacious in a mouse model of septicemia providing 100% protection from an otherwise lethal peritoneal infection of S. aureus Smith.

Application

Products | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Antibiotic

Product Information

• Catalog No.: HY-114622
• CAS No.: 1047981-31-6
• Molecular Formula: C29H29N3O6S
• Molecular Weight: 547.62
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source