LY256548 (LY25648) is an orally available anti-ischemic and anti-inflammatory compound with central nervous system activity. LY256548 is an inhibitor of phospholipase A2 , 5-lipoxygenase ( 5-LOX ), and COX , and inhibits A23187 ( HY-N6687 )-stimulated leukotriene B4 production. LY256548 inhibits bone damage and paw swelling in the rat Freund's complete adjuvant-induced arthritis (FCA) model.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Phospholipase | Products > Signaling Pathways > COX | Products > Signaling Pathways > Lipoxygenase | Products > Signaling Pathways > Leukotriene Receptor
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