tert-Butylchlorodiphenylsilane

tert-Butylchlorodiphenylsilane
  • CAS No.:58479-61-1
Other grades of this product :

Boiling point 90 °C0.01 mm Hg(lit.)
density 1.057 g/mL at 25 °C(lit.)
refractive index n20/D1.568(lit.)
Fp >230 °F
storage temp. Inert atmosphere,2-8°C
solubility miscible in most organic solvents.
form Liquid
color Clear colorless to yellow or slightly brown
Specific Gravity1.074
Water Solubility reacts
Sensitive Moisture Sensitive
Hydrolytic Sensitivity7: reacts slowly with moisture/water
BRN 644023
CAS DataBase Reference58479-61-1(CAS DataBase Reference)
NIST Chemistry ReferenceSilane, chloro(1,1-dimethylethyl)diphenyl-(58479-61-1)
EPA Substance Registry SystemSilane, chloro(1,1-dimethylethyl)diphenyl- (58479-61-1)

1. Silane protective agent, its function is to replace the active hydrogen in the silyl group (such as the hydrogen in the hydroxyl, carboxyl and amino groups) to generate a stable intermediate; then, other groups of the intermediate are carrying out certain reactions; After the reaction, through hydrolysis, the silyl group is removed, the group originally protected by the silyl group is regenerated, and some specific compounds are synthesized. Due to the high conversion rate and even quantitative reaction of silane protection and deprotection reactions, it is widely used in organic synthesis, especially in drug synthesis.

2. Silanating reagents for protecting alcohols and preparing silyl ethers

3. For the synthesis of p-benzophenyloxazole, which is a compound with antagonistic activity to thromboxane receptors, which can be used to treat circulatory system diseases, angina pectoris and stroke.

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