FKGK18

Overview

FKGK18 is a selective group VIA calcium-independent phospholipase A 2 (GVIA iPLA 2 ) inhibitor. FKGK18 is a fluoroketone (FK)-based compound with IC 50 s of 50 nM and 3 μM for iPLA 2 β and iPLA 2 γ. FKGK18 can be used for the research of beta-cell apoptosis and diabetes.

Application

Products | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Phospholipase | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-115403
• CAS No.: 1071001-09-6
• Molecular Formula: C16H15F3O
• Molecular Weight: 280.28
• Purity: 99.9%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.25 mg/mL (4.46 mM); Clear solution
• Availability: In-stock

Source

Original product source