GPVI antagonist 3 (Compound 2) is a potential antagonist of Glycoprotein VI ( GPVI ). IC 50 values of GPVI antagonist 3 are, respectively, 1.01 μM for collagen , 1.92 μM for CRP, 7.24 μM for convulxin and 51.74 μM for thrombin . Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 3 is a promising antiplatelet agent.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Glycoprotein VI
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