DENV-IN-4 is a potent DENV inhibitor (DENV EC 50 =4.79 μM, Vero CC 50 >100 μM, SI>20.9). DENV-IN-4 can inhibit the expression level of DENV2 with concentration-dependence and reduce RNA-dependent RNA polymerase (RdRp) enzymatic activity. DENV-IN-4 has antiviral effect.
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