SR-4554 is a probe for the measurement of tumor hypoxia. SR-4554 undergoes enzymatic single-electron reduction reactions within hypoxic cells. SR-4554 determines the 19 F retention index for four commonly used mouse tumors (EMT6, SCCVII, KILT and RIF-I) through 19 F MRS technique. SR-4554 can used to detect tumor Hypoxia noninvasively by 19 F magnetic resonance spectroscopy ( 19 F MRS).
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