AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate exhibits antiretroviral activity and inhibits replication of HIV . AZT triphosphate also inhibits the DNA polymerase of HBV . AZT triphosphate activates the mitochondria-mediated apoptosis pathway.
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