WR99210 hydrochloride is an orally active and low-toxicity dihydrofolate reductase (DHFR) inhibitor ( IC 50 <0.075 nM). WR99210 hydrochloride shows good antiparasitic activity and is effective against P. falciparum and P. falciparum strains as well as T. gondii .
Products | Products > Disease Areas > Infection | Products > Disease Areas > Parasitic Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Dihydrofolate reductase (DHFR) | Products > Signaling Pathways > Parasite
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