Viridicatol

Overview

Viridicatol is a quinolone alkaloid with anti-inflammatory, antibacterial , antifungal , osteogenic and chondrogenic activities. Viridicatol reduces the phosphorylation levels of ERK , JNK , p38 and STAT6 ; inhibits MMP-2 , MMP-9 , NF-κB signaling pathway and PTP1B ; downregulates genes related to mast cell activation; and binds to SHN3 to activate the Wnt/SHN3 signaling pathway. Viridicatol inhibits the expression of pro-inflammatory mediators and cytokines, and promotes osteogenic/chondrogenic differentiation. Viridicatol can be used in studies related to fibrosarcoma, allergy, bacterial infection , fungal infection and osteoporosis.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Mineral Metabolism | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Fungal Infection | Products > Disease Areas > Osteoporosis | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Signaling Pathways > JNK | Products > Signaling Pathways > MMP | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > STAT | Products > Signaling Pathways > Fungal | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > PGE synthase | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Wnt | Products > Signaling Pathways > β-catenin | Products > Signaling Pathways > ERK

Product Information

• Catalog No.: HY-116474
• CAS No.: 14484-44-7
• Molecular Formula: C15H11NO3
• Molecular Weight: 253.25
• Purity: 99.93%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (8.21 mM); Clear solution
• Availability: In-stock

Source

Original product source