TH1020

Overview

TH1020 is a potent and selective toll-like receptor 5 (TLR5)/flagellin complex antagonist with an IC 50 of 0.85 μM. TH1020 inhbits flagellin-induced TLR5 signaling. TH1020 is inactive against TLR2 , TLR3 , TLR4 , TLR7 and TLR8 .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Signaling Pathways > Toll-like Receptor (TLR) | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-116961
• CAS No.: 1841460-82-9
• Molecular Formula: C23H15N7S2
• Molecular Weight: 453.54
• Purity: 99.81%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 0.5 mg/mL (1.10 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source