GSK2945

Overview

GSK2945 is a class of tertiary amine, and is a highly specific Rev-erbα / REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist with EC 50 s of 21.5 μM and 20.8 μM, respectively. GSK2945 enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Cytochrome P450

Product Information

• Catalog No.: HY-117147
• CAS No.: 1438071-12-5
• Molecular Formula: C20H18Cl2N2O2S
• Molecular Weight: 421.34
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Solubility: ≥ 2.08 mg/mL (4.94 mM); Clear solution

Source

Original product source