MRS2693 trisodium is a selective P2Y6 agonist with an EC 50 value of 0.015 μM. MRS2693 trisodium can reduce the activation of NF-kappaB and activate the ERK1/2 pathway, and has a cytoprotective effect on mouse hindlimb skeletal muscle ischemia-reperfusion injury model.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > P2Y Receptor | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > ERK
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