HJC0123

Overview

HJC0123 is a STAT3 inhibitor. HJC0123 inhibits the proliferation of hepatic stellate cells and induces cell cycle arrest and apoptosis . HJC0123 reduces the phosphorylation, nuclear translocation and transcriptional activities of STAT3 , increases the production of IL-6 , inhibits the phosphorylation of Smad2/3 and down-regulates SOCS3 . HJC0123 can be used in the study of liver fibrosis.

Application

Products | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Others | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > STAT | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-117511
• CAS No.: 1430420-02-2
• Molecular Formula: C24H16N2O3S
• Molecular Weight: 412.46
• Purity: 99.06%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source