4010B-30 is a upregulator of apolipoprotein A-I ( ApoA-I ). 4010B-30 regulates ApoA-I gene expression through activation of PPARγ . 4010B-30 promotes cholesterol efflux and ABCA1 expression. 4010B-30 protects against atherosclerotic lesion development in ApoE -/- mice.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Apolipoprotein | Products > Signaling Pathways > PPAR | Products > Signaling Pathways > ATP-binding cassette (ABC) transporters
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