Ro 09-1428

CAS No.：134452-47-4
Grade：99.98%
Formula：C31H31N11O10S3
M.W.：813.84

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Overview

Ro 09-1428 is a broad-spectrum parenteral cephalosporin. Ro 09-1428 has potent antibacterial activities against Pseudomonas aeruginosa and Acinetobacter caloaceticus , with MIC90s of 0.39 and 6.25 μg/mL, respectively, better than Ceftazidime ( HY-B0593 ). Additionally, Ro 09-1428 shows high activity against Escherichia coli , Kkbsielia pneumoniae , Proteus mirabilis , P. aeruginosa , staphylococci , and more. Ro 09-1428 preferentially attacks PBP 3 for target in E. coli and P. aeruginosa , which is promising for research of septicemias and serious P. aeruginosa infections.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Signaling Pathways > Penicillin-binding protein (PBP) | Products > Signaling Pathways > Bacterial

Product Information

Catalog No.: HY-117736
CAS No.: 134452-47-4
Molecular Formula: C31H31N11O10S3
Molecular Weight: 813.84
Purity: 99.98%
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source

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