Keto-itraconazole

Overview

Keto-itraconazole (keto-ITZ) is a metabolism of Itraconazole ( HY-17514 ) with a potent inhibitor activity of CYP3A . Keto-itraconazole shows unbound IC 50 value of 4.6 nM when coincubated with human liver microsomes and midazolam.

Application

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Product Information

• Catalog No.: HY-117789
• CAS No.: 112560-33-5
• Molecular Formula: C35H36Cl2N8O5
• Molecular Weight: 719.62
• Purity: 98.4%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source