2-Thiouridine

Overview

2-Thiouridine is an orally active modified nucleobase. 2-Thiouridine stabilizes U:A base pairs and destabilizes U:G wobble base pairs. 2-Thiouridine significantly improves the efficiency and accuracy of nonenzymatic replication of mixed-sequence A/U-containing RNA templates. 2-Thiouridine exhibits antiviral activity against multiple positive-sense single-stranded RNA viruses ( DENV2 , ZIKV , YFV , JEV , WNV , CHIKV , human coronaviruses ( [HCoV]-229E , HCoV-OC43 , SARS-CoV ), and MERS-CoV ).

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Nucleoside Antimetabolite/Analog | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Dengue Virus | Products > Signaling Pathways > Flavivirus | Products > Signaling Pathways > CHIKV | Products > Signaling Pathways > SARS-CoV

Product Information

• Catalog No.: HY-117813
• CAS No.: 20235-78-3
• Molecular Formula: C9H12N2O5S
• Molecular Weight: 260.27
• Purity: 99.92%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source