KBP-7018 is an orally active, tyrosine kinase-selective multi-kinase inhibitor with an IC 50 value of 10 nM against c-KIT , 7.6 nM against RET , and 25 nM against human PDGFR . KBP-7018 improves survival rates in a mouse model of pulmonary fibrosis. KBP-7018 can be used in research related to idiopathic pulmonary fibrosis.
Products | Products > Disease Areas > Lung Fibrosis | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Pulmonary Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > c-Kit | Products > Signaling Pathways > RET | Products > Signaling Pathways > PDGFR | Products > Signaling Pathways > Cytochrome P450
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