SKI2496

Overview

SKI2496 is an orally active GnRH receptor antagonist ( IC 50 : 0.25 nM for hGnRHR, 13.2 nM for monkey GnRHR, 279.2 nM for rat GnRHR). SKI2496 blocks Ca 2+ flux with an IC 50 value of 0.76 nM. SKI2496 inhibits ERK1/2 phosphorylation with an IC 50 value of 2.6 nM. SKI2496 inhbits serum LH concentrations, and can be used for research of sex hormone-dependent disorders.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Endocrinology | Products > Signaling Pathways > GnRH Receptor | Products > Signaling Pathways > ERK

Product Information

• Catalog No.: HY-117982
• CAS No.: 1308378-95-1
• Molecular Formula: C35H36F7N5O5
• Molecular Weight: 739.68
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source