RU-505 is an effective β-amyloid ( Aβ )-fibrinogen interaction inhibitor with IC 50 s of 5.00 and 2.72 μM in fluorescence polarization ( FP ) and AlphaLISA assays, respectively. RU-505 is highly permeable to the BBB. RU-505 reduces cerebral amyloid angiopathy (CAA). RU-505 can be used for the research of Alzheimer’s disease (AD).
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