GSK2245035 maleate

Overview

GSK2245035 maleate is a highly potent and selective intranasal Toll-Like receptor 7 ( TLR7 ) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 maleate has pEC 50 s of 9.3 and 6.5 for IFNα and TFNα. GSK2245035 maleate effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures. GSK2245035 maleate is used for asthma.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Toll-like Receptor (TLR) | Products > Signaling Pathways > IFNAR | Products > Signaling Pathways > TNF Receptor

Product Information

• Catalog No.: HY-118250A
• CAS No.: 1325212-97-2
• Molecular Formula: C24H38N6O6
• Molecular Weight: 506.60
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source