Bis(maltolato)oxovanadium(IV) (BMOV) is a potent, reversible, competitive and orally active pan- PTP ( protein tyrosine phosphatases ) inhibitor. Bis(maltolato)oxovanadium(IV) inhibits HCPTPA , PTP1B , HPTPβ and SHP2 with IC 50 s of 126 nM, 109 nM, 26 nM and 201 nM, respectively. Bis(maltolato)oxovanadium(IV) is a potent insulin sensitizer.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Obesity | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > SHP2 | Products > Signaling Pathways > Phosphatase
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