ICRF-196

Overview

ICRF-196 is an racemic mixture of the (S,S)- and (R,R)-isomers of ICRF-193 ( HY-118590 ). ICRF-193 is a DNA Topoisomerase II inhibitor. ICRF-193 can inhibit DNA syntheses and induces apoptosis . ICRF-193 exhibits anti-cancer and anti-inflammation effects. ICRF-193 shows cardioprotective effect against anthracycline toxicity to cardiomyocytes. ICRF-193 can be used for the researches of cancer , infection , inflammation and cardiovascular disease , such as acute promyelocytic leukemia.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Topoisomerase | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Fungal

Product Information

• Catalog No.: HY-118590A
• CAS No.: 21416-68-2
• Molecular Formula: C12H18N4O4
• Molecular Weight: 282.30
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source