VU041

Overview

VU041 is a first submicromolar-affinity inhibitor of Anopheles (An.) gambiae and Aedes (Ae.) aegypti inward rectifier potassium 1 (Kir1) channels with IC 50 values of 2.5 μM and 1.7 μM, respectively. VU041 inhibits appreciably is mammalian Kir2.1 ( IC 50 of 12.7 μM), and has less inhibitory effect on mammalian Kir1.1, Kir4.1, Kir6.2/SUR1, and Kir7.1. VU041 also induces impaired Malpighian tubule function.

Application

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Product Information

• Catalog No.: HY-118607
• CAS No.: 332943-64-3
• Molecular Formula: C19H20F3N3O
• Molecular Weight: 363.38
• Purity: 99.81%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2 mg/mL (5.50 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source