LAF389

Overview

LAF389, a prodrug of LAF153 ( HY-183876 ), is a methionine aminopeptidase ( MetAps ) inhibitor with an IC 50 of 800 nM against MetAp2 , and exhibits a maximum inhibition rate of 20% against MetAp1 at 300 nM. LAF389 possesses antiproliferative, antiangiogenic and cytotoxic activities. LAF389 can be used in research related to cancers such as advanced solid tumors.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Others | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Signaling Pathways > MetAP | Products > Signaling Pathways > Drug Intermediate

Product Information

• Catalog No.: HY-118953
• CAS No.: 270902-51-7
• Molecular Formula: C25H42N2O8
• Molecular Weight: 498.61
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source