BMS-199264 hydrochloride is an inhibitor of F1F0 ATP hydrolase ( IC 50 =0.5 μM) without inhibitory effect on F1F0 ATP synthase . BMS-199264 hydrochloride selectively inhibits ATP decline during ischemia to reduces cardiac necrosis. BMS-199264 hydrochloride also enhances the recovery of contractile function following reperfusion.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > ATP Synthase
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